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Tesamorelin
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Research Use Only
Research Use Only - All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
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Tesamorelin
Overview
Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH), studied for its role in GH secretion, metabolic regulation, and visceral adiposity in experimental models. It activates GHRH receptors in the pituitary, leading to the synthesis and release of growth hormone. This peptide has been investigated for its potential to influence body composition and metabolic parameters in research settings. In: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet].
Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012. 2018 Oct 20.
History
Tesamorelin, a synthetic GHRH, was developed as a potential treatment for various conditions associated with growth hormone deficiency. Early research focused on its ability to stimulate endogenous growth hormone secretion. Its development aimed to improve stability and pharmacokinetics compared to native GHRH, leading to its evaluation in clinical studies.
Tesamorelin
Structure
Molecular Formula:
C153H250N30O39S6
Molecular Weight:
3326.2 g/mol
PubChem ID:
16136075
Research Findings
Research into Tesamorelin has explored its multifaceted effects on various physiological systems, particularly in the context of metabolic health and body composition. Studies have focused on its capacity to modulate growth hormone pathways and influence fat distribution.
Key Areas of Research:
Visceral Adiposity: Reduction of visceral adipose tissue (VAT) in experimental models
Metabolic Regulation: Improvements in lipid profiles, including triglycerides and cholesterol to high-density lipoprotein ratio
Growth Hormone Secretion: Stimulation of endogenous growth hormone release and increase in IGF-1 levels
Body Composition: Preservation of abdominal subcutaneous adipose tissue and overall positive impact on body image
These findings highlight Tesamorelin’s potential as a research tool for investigating metabolic and endocrine functions, offering insights into novel therapeutic strategies.
References
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All products are for research use only. Third-party testes for 99%+ purity.
